Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307179 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL1306700 | 0.93 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL1306696 | 0.93 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL1306109 | 0.92 | HPGD (0.48) | ALDH1A1MEN1KMT2ACNR2CNR1 | |
| SCHEMBL1306108 | 0.92 | HPGD (0.48) | ALDH1A1MEN1KMT2ACNR2CNR1 | |
| SCHEMBL1305400 | 0.91 | CACNA1B (0.46) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL1305933 | 0.91 | CACNA1B (0.46) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL29488457 | 0.91 | CACNA1B (0.46) | ALDH1A1KDM4EMEN1KMT2ACACNA1B | |
| SCHEMBL1306518 | 0.89 | CNR2 (0.41) | ALDH1A1KDM4ECNR2CNR1HPGD | |
| SCHEMBL1306519 | 0.89 | CNR2 (0.41) | ALDH1A1KDM4ECNR2CNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |