Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22550059 | 0.93 | HRH3 (0.61) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL25137036 | 0.89 | HRH3 (0.62) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL15467001 | 0.86 | HRH3 (0.87) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL301839 | 0.85 | HRH3 (0.71) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL16644362 | 0.83 | HRH3 (0.69) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL16644328 | 0.83 | HRH3 (0.69) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL10244180 | 0.83 | NCF1 (0.67) | HRH3SMN1; SMN2NOS1MAPTALDH1A1 | |
| SCHEMBL13228061 | 0.82 | HRH3 (0.68) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL15391995 | 0.81 | HRH3 (0.67) | HRH3SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL27630736 | 0.81 | HRH3 (0.67) | HRH3SMN1; SMN2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640533-B2 | Epoxyketone compounds for enzyme inhibition | CENTRAX INTERNATIONAL, INC. (US) | 2020-05-05 | — | — | US | disclosed |
| EP-3332645-A1 | USE OF SUBSTITUTED PYRIMIDINE DIONES OR THEIR SALTS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | Bayer Cropscience AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| US-20170158734-A1 | EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION | CENTRAX INTERNATIONAL, INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-20100317644-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317644-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | HRH3 1271/4885SMN1; SMN2 45/4885NOS3 2108/4885 |
| US-10640533-B2 | Epoxyketone compounds for enzyme inhibition | PSMD10, PSMC1, PSMB10 | HRH3 4156/4885SMN1; SMN2 1323/4885NOS3 3196/4885 |
| US-20170158734-A1 | EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION | PSMD10, PSMC1, PSMB10 | HRH3 4156/4885SMN1; SMN2 1323/4885NOS3 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.