SCHEMBL1306139

SCHEMBL1306139

CCN(CC)c1ccc(C(=O)C(=O)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
POLB P06746 4/20 0.58
NOX1 Q9Y5S8 2/20 0.58
GAA P10253 2/20 0.58
MCL1 Q07820 1/20 0.58
ALDH1A1 P00352 7/20 0.54
ALDH3A1 P30838 1/20 0.54
ALDH1A3 P47895 1/20 0.54
KDM4E B2RXH2 1/20 0.53
HTT P42858 1/20 0.53
MAPK1 P28482 3/20 0.52
RECQL P46063 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
PSMD14 O00487 1/20 0.52
CYP3A4 P08684 1/20 0.52
GFER P55789 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16561453 0.92 ESRRG (0.59) MAPTMEN1KMT2APOLBNOX1
SCHEMBL14982110 0.92 RAB9A (0.63) MAPTMEN1KMT2APOLBNOX1
SCHEMBL8695963 0.92 RAB9A (0.63) MAPTMEN1KMT2APOLBNOX1
SCHEMBL16561450 0.90 MAPT (0.63) MAPTMEN1KMT2APOLBNOX1
SCHEMBL8695005 0.90 ALDH1A1 (0.70) MAPTMEN1KMT2APOLBNOX1
SCHEMBL9321348 0.90 MAPT (0.57) MAPTMEN1KMT2APOLBNOX1
SCHEMBL3828643 0.87 MAPT (0.59) MAPTMEN1KMT2APOLBNOX1
SCHEMBL61950 0.86 ALDH1A1 (0.58) MAPTMEN1KMT2APOLBNOX1
SCHEMBL6569210 0.84 MAPT (0.56) MAPTMEN1KMT2APOLBNOX1
SCHEMBL64440 0.84 MEN1 (0.56) MAPTMEN1KMT2APOLBNOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9535347-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-01-03 US disclosed
US-20140363759-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2014-12-11 US disclosed
US-20140363759-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2014-12-11 US disclosed
US-8841052-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-8841052-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20130137023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-20130137023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-8053573-B2 Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-11-08 US disclosed
US-5756527-A ANTICARCINOGENIC AGENTS ONTOGEN CORPORATION (US) 1998-05-26 US disclosed
US-5738974-A PHOTOPOLYMERIZABLE COMPOSITION, INITIATOR COMPRISING TITANOCENE COMPOUND AND COUMARIN COMPOUND ON ANODIZED ALUMINUM SUBSTRATE MITSUBISHI CHEMICAL CORPORATION (JP) 1998-04-14 US disclosed
EP-0704764-B1 Photopolymerizable composition and photosensitive lithographic printing plate MITSUBISHI CHEM CORP (JP) 1998-03-25 EP disclosed
EP-0812830-A1 Modulators of multi-drug resistances ONTOGEN CORPORATION (US) 1997-12-17 EP disclosed
EP-0704764-A1 Photopolymerizable composition and photosensitive lithographic printing plate MITSUBISHI CHEMICAL CORPORATION (JP) 1996-04-03 EP disclosed
US-5164512-A Triarylimidazole derivative, determination of hydrogen peroxide generated by enzymatic reaction WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-17 US disclosed
EP-0404526-A1 Oxidizable color producing reagent WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-12-27 EP disclosed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
EP-0166230-B1 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-06 EP disclosed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 EP disclosed