Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895820 | 0.92 | P2RX3 (0.45) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL1306221 | 0.91 | P2RX3 (0.49) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL1306159 | 0.78 | P2RX3 (0.50) | P2RX3ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL1307039 | 0.78 | ALDH1A1 (0.51) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL1307038 | 0.78 | ALDH1A1 (0.51) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL12113377 | 0.78 | ALDH1A1 (0.51) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL3822470 | 0.75 | P2RX3 (0.63) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL1305453 | 0.74 | P2RX3 (0.46) | P2RX3ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL3813132 | 0.74 | ALDH1A1 (0.41) | P2RX3ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL3821001 | 0.74 | P2RX3 (0.48) | P2RX3ALDH1A1KDM4ETSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |