Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015758 | 1.00 | APP (0.47) | APPMAPTHDAC8TPMTCA1 | |
| SCHEMBL2037596 | 0.91 | APP (0.48) | APPMAPTTPMT | |
| SCHEMBL16501329 | 0.88 | APP (0.67) | APPMAPTCA1CA2KDM4E | |
| SCHEMBL16675523 | 0.86 | CYP1A1 (0.50) | APPMAPTHDAC8CA1CA2 | |
| SCHEMBL21564900 | 0.86 | GRM5 (0.52) | APPMAPTCA1CA2MEN1 | |
| SCHEMBL16675512 | 0.86 | CYP1A1 (0.50) | APPMAPTHDAC8CA1CA2 | |
| SCHEMBL2865734 | 0.86 | APP (0.74) | APPMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL5484564 | 0.84 | APP (0.41) | APPHDAC8TPMT | |
| SCHEMBL3431838 | 0.82 | APP (0.39) | APP | |
| SCHEMBL9333106 | 0.82 | CYP1A1 (0.52) | APPMAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46426-E1 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-8289494-B2 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2012-10-16 | — | — | US | disclosed |
| US-8053588-B2 | organosilane compounds used as raw materials for synthesis of organosilicon polymer thin films, having a refractive-index controlling function, a light absorbing function, a light emitting function, and a charge transferring function | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2011-11-08 | — | — | US | disclosed |
| US-8053588-B2 | organosilane compounds used as raw materials for synthesis of organosilicon polymer thin films, having a refractive-index controlling function, a light absorbing function, a light emitting function, and a charge transferring function | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2129743-B1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| EP-2129743-A1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | Merck Patent GmbH (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008119427-A1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2008-10-09 | — | — | WO | disclosed |
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
| US-5876830-A | Method of assembly of molecular-sized nets and scaffolding | BOARD OF REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PUF60, LCP1, MAP1LC3C | APP 1198/4885MAPT 16/4885HDAC8 4644/4885 |
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | CARM1, PRMT1, PRMT8 | APP 4377/4885MAPT 4797/4885HDAC8 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.