SCHEMBL5484564

SCHEMBL5484564

IC#Cc1ccc(I)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.41
TPMT P51580 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484562 0.87 APP (0.42) APP
SCHEMBL20015758 0.84 APP (0.47) APPTPMTHDAC8
SCHEMBL1306241 0.84 APP (0.47) APPTPMTHDAC8
SCHEMBL18649211 0.77 APP (0.41) APPTPMTHDAC8
SCHEMBL2037596 0.77 APP (0.48) APPTPMT
SCHEMBL3431838 0.74 APP (0.39) APP
SCHEMBL9333106 0.74 CYP1A1 (0.52) APPHDAC8
SCHEMBL4597614 0.74 GRM5 (0.39) APP
SCHEMBL28408406 0.74 CA2 (0.48) HDAC8
SCHEMBL16501329 0.74 APP (0.67) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263732-B2 Photo-alignment film and liquid crystal display element JNC CORPORATION (JP) 2012-09-11 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed