Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367962 | 0.82 | KDM4E (0.37) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11738097 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1873244 | 0.80 | SLC6A3 (0.36) | SMN1; SMN2SLC6A2 | |
| SCHEMBL1876064 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7480714 | 0.77 | KDM4E (0.38) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8183357 | 0.76 | KDM4E (0.37) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16563720 | 0.76 | KDM4E (0.42) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2082072 | 0.74 | CNR1 (0.40) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5732853 | 0.74 | KDM4E (0.34) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2286730 | 0.74 | KDM1A (0.42) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541823-B | Progesterone receptor antagonists | BAYER SCHERING PHARMA AG | 2012-10-03 | — | — | CN | disclosed |
| US-8053426-B2 | Such as 11-beta-[4-(1,2-Dihydroxyethyl)phenyl]-20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17 alpha-pregna-4,9-dien-3-one or corresponding 4-(hydroxyacetyl)phenyl derivative thereof; endometriosis, myomas or hormone-dependent tumors, such as breast cancer | BAYER SCHERING PHARMA AG (DE) | 2011-11-08 | — | — | US | disclosed |
| EP-2081951-B1 | PROGESTERONE RECEPTOR ANTAGONISTS | BAYER SCHERING PHARMA AG (DE) | 2010-04-21 | — | — | EP | disclosed |
| CN-101541823-A | Progesterone receptor antagonists | BAYER SCHERING PHARMA AG (DE) | 2009-09-23 | — | — | CN | disclosed |
| EP-2081951-A1 | PROGESTERONE RECEPTOR ANTAGONISTS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-07-29 | — | — | EP | disclosed |
| US-20080200440-A1 | Progesterone receptor antagonists | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
| WO-2008058767-A1 | PROGESTERONE RECEPTOR ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200440-A1 | Progesterone receptor antagonists | PGR, PGRMC2, GNRHR | ALDH1A1 1288/4885KDM4E 3358/4885CYP1A2 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.