Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.70 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.64 |
| ▸ | CCKAR | P32238 | 5/20 | 0.63 |
| ▸ | GABRP | O00591 | 1/20 | 0.63 |
| ▸ | GABRD | O14764 | 1/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.63 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.63 |
| ▸ | GABRE | P78334 | 1/20 | 0.63 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.63 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.63 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.63 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547267 | 0.86 | CCKBR (0.57) | CCKBRSCN9ACCKAR | |
| SCHEMBL8545924 | 0.84 | SENP1 (0.52) | CCKBRSCN9ACCKAR | |
| SCHEMBL8610053 | 0.83 | CCKBR (0.80) | CCKBRSCN9ACCKAR | |
| SCHEMBL9868116 | 0.83 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9868120 | 0.83 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9866762 | 0.82 | CCKBR (1.00) | CCKBR | |
| SCHEMBL2927644 | 0.82 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL7207460 | 0.82 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL4189616 | 0.82 | CCKBR (0.77) | CCKBRSCN9ACCKAR | |
| SCHEMBL4189611 | 0.82 | CCKBR (0.77) | CCKBRSCN9ACCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231623-B1 | 5-PHENYL-1H-BENZO[E][1, 4]DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS | UNIV FIRENZE (IT) | 2013-05-22 | — | — | EP | disclosed |
| US-8324202-B2 | 5-phenyl-1H-benzo [E] [1,4] diazepine compounds substituted with an hydroxamic acid group as histone deacetylase inhibitors | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2012-12-04 | — | — | US | disclosed |
| US-20100331316-A1 | 5-PHENYL-LH-BENZ0 [E] [1,4] DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS | A.I.L. FIRENZE SEZIONE AUTONOMA DI FIRENZE DELL'ASSOCIAZIONE ITALIANA CONTRO LE LEUCEMIE, LINFOMI E MIELOMA - ONLUS (IT) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331316-A1 | 5-PHENYL-LH-BENZ0 [E] [1,4] DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS | HDAC10, HDAC1, HDAC5 | CCKBR 2021/4885SCN9A 2811/4885CCKAR 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.