Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976762 | 0.81 | — | — | |
| SCHEMBL21654166 | 0.79 | TSHR (0.42) | TSHR | |
| SCHEMBL28202544 | 0.79 | DPP7 (0.35) | TSHRSPHK1DPP7RRM1 | |
| SCHEMBL27349632 | 0.74 | SPHK1 (0.47) | TSHRSPHK1DPP7RRM1 | |
| SCHEMBL22877768 | 0.73 | TSHR (0.44) | TSHR | |
| SCHEMBL819835 | 0.72 | — | — | |
| SCHEMBL4310720 | 0.70 | — | — | |
| SCHEMBL976799 | 0.69 | DNM1 (0.39) | TSHRSPHK1DPP7RRM1 | |
| SCHEMBL18664296 | 0.69 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL13707476 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259061-A2 | Boronic acid derivatives | The Regents of The University of California (US) | 2010-12-08 | — | — | EP | disclosed |