Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19262987 | 0.86 | TSHR (0.64) | EPHX2NR1H4ALDH1A1TSHRCYP1A2 | |
| SCHEMBL1664008 | 0.84 | POLB (0.53) | EPHX2NR1H4ALDH1A1HDAC4HDAC6 | |
| SCHEMBL9995304 | 0.83 | CYP1A2 (0.51) | EPHX2NR1H4ALDH1A1TSHRCYP1A2 | |
| SCHEMBL9625733 | 0.82 | EPHX2 (0.51) | EPHX2NR1H4ALDH1A1TSHRCYP1A2 | |
| SCHEMBL10050998 | 0.82 | KDM4E (0.57) | EPHX2NR1H4ALDH1A1TSHRBLM | |
| SCHEMBL25018799 | 0.81 | CYP1A2 (0.54) | EPHX2NR1H4ALDH1A1TSHRCYP1A2 | |
| SCHEMBL12641858 | 0.81 | GAA (0.57) | EPHX2NR1H4ALDH1A1HDAC6MAPK1 | |
| SCHEMBL2646881 | 0.81 | CA1 (0.58) | EPHX2NR1H4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL2646800 | 0.81 | CA1 (0.58) | EPHX2NR1H4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL15652257 | 0.81 | EPHX2 (0.54) | EPHX2NR1H4ALDH1A1TSHRHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133851-A1 | PREPARATION OF LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |