Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320271 | 0.78 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL8284499 | 0.78 | ELANE (0.34) | DGAT1 | |
| Hydrochloric Acid SCHEMBL485921 | 0.76 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL18894916 | 0.74 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL25238443 | 0.71 | FDPS (0.32) | DGAT1 | |
| SCHEMBL607878 | 0.71 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL10115920 | 0.70 | CYP4F2 (0.31) | — | |
| SCHEMBL20576998 | 0.69 | — | — | |
| SCHEMBL607879 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL9006777 | 0.69 | GAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266971-A2 | Hiv protease inhibiting compounds | Abbott Laboratories (US) | 2010-12-29 | — | — | EP | disclosed |