Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595584 | 1.00 | KDM4A (0.47) | KDM4AKDM4CNAMPTLMNAEPHX1 | |
| SCHEMBL14073785 | 1.00 | KDM4A (0.47) | KDM4AKDM4CNAMPTLMNAEPHX1 | |
| SCHEMBL19267180 | 0.98 | LMNA (0.46) | KDM4AKDM4CNAMPTLMNAEPHX1 | |
| SCHEMBL23616303 | 0.92 | CASP2 (0.52) | NAMPTFAAHCASP2MEN1KMT2A | |
| SCHEMBL2742896 | 0.90 | — | — | |
| SCHEMBL21501444 | 0.88 | GAA (0.47) | KDM4AKDM4CNAMPTLMNAEPHX1 | |
| Hydrochloric Acid SCHEMBL2022572 | 0.88 | LMNA (0.46) | KDM4AKDM4CNAMPTLMNAEPHX1 | |
| SCHEMBL5909431 | 0.87 | HDAC3 (0.55) | NAMPTLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL5909483 | 0.87 | HDAC3 (0.55) | NAMPTLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL12333287 | 0.87 | HDAC3 (0.55) | NAMPTLMNAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494705-B1 | A COMPOSITION AND METHOD FOR KILLING OF TUMOURS | COMMW SCIENT IND RES ORG (AU) | 2010-12-29 | — | — | EP | disclosed |