⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2022572 | 0.97 | LMNA (0.46) | — | |
| SCHEMBL19267180 | 0.92 | LMNA (0.46) | — | |
| SCHEMBL15306198 | 0.91 | TSHR (0.48) | — | |
| SCHEMBL14073785 | 0.90 | KDM4A (0.47) | — | |
| SCHEMBL13595584 | 0.90 | KDM4A (0.47) | — | |
| SCHEMBL13063685 | 0.90 | KDM4A (0.47) | — | |
| SCHEMBL464448 | 0.83 | — | — | |
| SCHEMBL18477609 | 0.83 | LMNA (0.43) | — | |
| SCHEMBL5909180 | 0.83 | LMNA (0.57) | — | |
| SCHEMBL7753090 | 0.83 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265620-A1 | NOVEL CAMPTOTHECIN DERIVATIVE, COMPOSITION CONTAINING SAME, AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-20230331760-A1 | ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG | SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
| EP-4186888-A1 | COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ModernaTX, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11332491-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3526239-B1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORP (KR) | 2021-11-03 | — | — | EP | disclosed |
| US-20210017215-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
| US-10766916-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20200157134-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2020-05-21 | — | — | US | disclosed |
| US-20190345202-A1 | ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2019-11-14 | — | — | US | disclosed |
| WO-2018069764-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2018-04-19 | — | — | WO | disclosed |
| WO-2010067886-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-06-17 | — | — | WO | disclosed |
| US-7728117-B2 | Heterobifunctional pan-selectin inhibitors | GLYCOMIMETICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20090312278-A1 | TREATMENT OF CANCERS OF THE BLOOD USING SELECTED GLYCOMIMETIC COMPOUNDS | GLYCOMIMETICS , INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090253646-A1 | PAN-SELECTIN INHIBITOR WITH ENHANCED PHARMACOKINETIC ACTIVITY | GLYCOMIMETICS, INC. (US) | 2009-10-08 | — | — | US | disclosed |
| US-20090175792-A1 | GLYCOMIMETIC INHIBITORS OF SIGLEC-8 | GLYCOMIMETICS, INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20090036386-A1 | Heterobifunctional compounds for selectin inhibition | GLYCOMIMETICS, INC (US) | 2009-02-05 | — | — | US | disclosed |
| US-20090023679-A1 | Compounds and methods for treatment of sickle cell disease or complications associated therewith | GLYCOMIMETICS, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| US-20080200406-A1 | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines | GLYCOMIMETICS, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20080161546-A1 | Glycomimetic replacements for hexoses and N-acetyl hexosamines | GLYCOMIMETICS, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-7361644-B2 | Specific antagonist for both E- and P-selectins | GLYCOMIMETICS, INC. (US) | 2008-04-22 | — | — | US | disclosed |