⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064012 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL13175341 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL13063747 | 0.77 | — | — | |
| SCHEMBL29690175 | 0.76 | — | — | |
| SCHEMBL14520682 | 0.76 | — | — | |
| SCHEMBL14535252 | 0.76 | — | — | |
| SCHEMBL20197656 | 0.75 | — | — | |
| SCHEMBL14435597 | 0.74 | MAPK1 (0.37) | — | |
| SCHEMBL1508185 | 0.74 | — | — | |
| SCHEMBL13063741 | 0.71 | ADRB2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127159-A2 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127154-A1 | POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |