⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21287063 | 0.91 | CA12 (0.52) | — | |
| Ether SCHEMBL29118951 | 0.87 | CA12 (0.59) | — | |
| SCHEMBL239490 | 0.87 | ALDH1A1 (0.45) | — | |
| SCHEMBL8330702 | 0.86 | KDM4E (0.41) | — | |
| SCHEMBL8015113 | 0.84 | CA12 (0.62) | — | |
| Hydrochloric Acid SCHEMBL1965268 | 0.84 | ALDH1A1 (0.43) | — | |
| SCHEMBL9065706 | 0.83 | CA12 (0.48) | — | |
| SCHEMBL5932974 | 0.82 | KDM4E (0.40) | — | |
| SCHEMBL5932552 | 0.82 | KDM4E (0.40) | — | |
| SCHEMBL10962985 | 0.81 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844052-B2 | LLS compounds for treatment of cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190256503-A1 | LLS COMPOUNDS FOR TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-22 | — | — | US | disclosed |
| US-10338436-B2 | Method of manufacturing curved liquid crystal display device and curved liquid crystal display device | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-02 | — | — | US | disclosed |
| US-20180081243-A1 | METHOD OF MANUFACTURING CURVED LIQUID CRYSTAL DISPLAY DEVICE AND CURVED LIQUID CRYSTAL DISPLAY DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20170190708-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. | 2017-07-06 | — | — | US | disclosed |
| WO-2010127159-A2 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127154-A1 | POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |
| EP-2014285-B1 | NPYY5 antagonists | SHIONOGI & CO (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |