SCHEMBL167980

SCHEMBL167980

Cc1nc(C(F)F)c(C(=O)Nc2ccccc2-c2ccc(Br)cc2)s1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
HTT P42858 3/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RAB9A P51151 2/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.37
XIAP P98170 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437136 1.00 MAPT (0.41) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL13064249 0.91 TSHR (0.50) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL13210721 0.90 NTRK1 (0.43) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL1044642 0.90 MAPT (0.45) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL13210713 0.89 MAPT (0.41) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL343339 0.89 TDP1 (0.47) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL121792 0.87 ABCG2 (0.47) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL29419103 0.87 ABCG2 (0.47) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL13210812 0.87 MAPT (0.40) MAPTHTTPOLBTSHRHSD17B10
SCHEMBL20514734 0.87 ALDH1A1 (0.41) MAPTHTTPOLBTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163142-B2 Methods for manufacturing plant messenger packs FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-12-10 US claimed
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
US-20220064661-A1 AGRICULTURAL COMPOSITIONS AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-03-03 US claimed
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3381289-B1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BAYER CROPSCIENCE LP (US) 2021-05-05 EP claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP claimed
EP-3510869-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2019-07-17 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
EP-1819223-B1 USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS BASF SE (DE) 2008-03-12 EP claimed
US-20080039320-A1 Use Of Menadione BASF AKTIENGESELLSCHAFT (DE) 2008-02-14 US claimed
WO-2007122264-A2 COMPOSITION COMPRISING A GLUCAN OR A GLUCAN DERIVATIVE AND A PESTICIDE AND METHODS FOR IMPROVING PLANT HEALTH BASF SE (DE) 2007-11-01 WO claimed
EP-1849364-A1 Composition comprising a glucan or a glucan derivative and a pesticide and methods for improving plant health BASF AKTIENGESELLSCHAFT (DE) 2007-10-31 EP claimed
WO-2007104669-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2007-09-20 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
WO-2007101547-A2 SYNERGISTIC COMBINATIONS OF ACTIVE INGREDIENTS BAYER CROPSCIENCE AG (DE) 2007-09-13 WO claimed
US-20070060579-A1 Synergistic fungicidal active substance combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039320-A1 Use Of Menadione MANBA, MGAM2, MGAM MAPT 4216/4885HTT 4804/4885POLB 1094/4885
US-20070060579-A1 Synergistic fungicidal active substance combinations CYP51A1, CYP1A2, CYP4X1 MAPT 4345/4885HTT 4694/4885POLB 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.