Sugi Predict

Sugi Predict / Compounds / SCHEMBL343339

SCHEMBL343339

SCHEMBL343339

Cc1nc(C(F)F)c(C(=O)Nc2ccccc2-c2ccc(Cl)cc2)s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.47
▸ SUCNR1 Q9BXA5 3/20 0.45
▸ F10 P00742 2/20 0.42
▸ KMT2A Q03164 4/20 0.42
▸ HTT P42858 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ PLA2G1B P04054 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ NPY1R P25929 1/20 0.42
▸ NPY2R P49146 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ ATG4B Q9Y4P1 1/20 0.42
▸ MAPT P10636 3/20 0.41
▸ POLB P06746 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13064249 0.91 TSHR (0.50) KMT2AHTTGAALMNAMAPT
SCHEMBL1044642 0.90 MAPT (0.45) KMT2AHTTSMN1; SMN2GAALMNA
SCHEMBL13210721 0.90 NTRK1 (0.43) KMT2AHTTSMN1; SMN2LMNATHRB
SCHEMBL167980 0.89 MAPT (0.41) KMT2AHTTGAALMNANPSR1
SCHEMBL13210713 0.89 MAPT (0.41) KMT2AHTTSMN1; SMN2GAALMNA
SCHEMBL29437136 0.89 MAPT (0.41) KMT2AHTTGAALMNANPSR1
SCHEMBL2906748 0.89 CHRNA7 (0.47) KMT2AHTTGAAMAPTRAB9A
SCHEMBL13210784 0.89 KMT2A (0.42) SUCNR1KMT2AHTTSMN1; SMN2GAA
SCHEMBL14160059 0.88 RAB9A (0.42) KMT2AHTTSMN1; SMN2GAANPSR1
SCHEMBL12212662 0.88 MAPT (0.43) KMT2AHTTSMN1; SMN2GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140213557-A1 Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2014-07-31 — — US claimed
US-20110152097-A1 Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2011-06-23 — — US claimed
EP-2255651-A2 Agent combinations Bayer CropScience AG (DE) 2010-12-01 — — EP claimed
EP-2255644-A2 Agent combinations Bayer CropScience AG (DE) 2010-12-01 — — EP claimed
US-20100190645-A1 SYNERGISTIC FUNGICIDAL ACTIVE COMPOUND COMBINATIONS COMPRISING FORMONONETIN PLANT HEALTH CARE, INC. 2010-07-29 — — US claimed
US-20090280981-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-11-12 — — US claimed
US-20090105311-A1 Carboxamides BAYER CROPSCIENCE AG (DE) 2009-04-23 — — US claimed
US-20090018015-A1 Synergistic Fungicidal Active Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-15 — — US claimed
US-20080269263-A1 Synergistic Fungidical Active Substance Combinations BAYER CROPSCIENCE AG (DE) 2008-10-30 — — US claimed
US-20190174759-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-06-13 — — US disclosed
US-20190174759-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-06-13 — — US disclosed
US-10244755-B2 Fungicidal active compound combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-02 — — US disclosed
US-10244755-B2 Fungicidal active compound combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-02 — — US disclosed
EP-1802197-B1 FUNGICIDAL COMBINATIONS OF ACTIVE INGREDIENTS BAYER IP GMBH (DE) 2018-02-28 — — EP disclosed
WO-2007104437-A1 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-09-20 — — WO disclosed
WO-2007101547-A2 SYNERGISTIC COMBINATIONS OF ACTIVE INGREDIENTS BAYER CROPSCIENCE AG (DE) 2007-09-13 — — WO disclosed
WO-2007031141-A1 SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING A CARBOXAMIDE, AN AZOLE, A SECOND AZOLE OR A STROBILURINE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-22 — — WO disclosed
WO-2007031141-A1 SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING A CARBOXAMIDE, AN AZOLE, A SECOND AZOLE OR A STROBILURINE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-22 — — WO disclosed
US-20070060579-A1 Synergistic fungicidal active substance combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-15 — — US disclosed
US-20060128769-A1 Thiazoyl biphenyl amides BAYER CROPSCIENCE AG (DE) 2006-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190174759-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS DDT, CYP4X1, CYP51A1 TDP1 1269/4885SUCNR1 1704/4885F10 4773/4885
US-20060128769-A1 Thiazoyl biphenyl amides MRPL21, Q6ZSR9, DDT TDP1 1591/4885SUCNR1 984/4885F10 2899/4885
US-20110152097-A1 Active Compound Combinations AGXT, GLUL, GMNN TDP1 2738/4885SUCNR1 2936/4885F10 4344/4885
US-20080269263-A1 Synergistic Fungidical Active Substance Combinations ERG28, MANBA, MAN2A1 TDP1 3992/4885SUCNR1 206/4885F10 3465/4885
US-20090018015-A1 Synergistic Fungicidal Active Combinations CYP51A1, CYP1A2, CYP3A7 TDP1 1463/4885SUCNR1 531/4885F10 3592/4885
US-10244755-B2 Fungicidal active compound combinations DDT, CYP4X1, CYP51A1 TDP1 1269/4885SUCNR1 1704/4885F10 4773/4885
US-20090105311-A1 Carboxamides NAAA, CBR3, CNR1 TDP1 2497/4885SUCNR1 349/4885F10 2329/4885
US-20140213557-A1 Active Compound Combinations AGXT, GLUL, GMNN TDP1 2738/4885SUCNR1 2936/4885F10 4344/4885
US-20070060579-A1 Synergistic fungicidal active substance combinations CYP51A1, CYP1A2, CYP4X1 TDP1 2171/4885SUCNR1 140/4885F10 2819/4885
US-20100190645-A1 SYNERGISTIC FUNGICIDAL ACTIVE COMPOUND COMBINATIONS COMPRISING FORMONONETIN CYP51A1, ERG28, CYP3A7 TDP1 3874/4885SUCNR1 2969/4885F10 1577/4885
US-20090280981-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS CYP51A1, ERG28, CYP4X1 TDP1 2604/4885SUCNR1 2488/4885F10 3422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.