Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.57 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189346 | 0.91 | LMNA (0.85) | MEN1KMT2ALMNAALDH1A1PTGES | |
| SCHEMBL2246857 | 0.88 | MEN1 (0.65) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL2122421 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL1711098 | 0.86 | MEN1 (0.76) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL13065008 | 0.86 | TP53 (0.62) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL13064516 | 0.85 | LMNA (0.60) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL13065202 | 0.84 | CNR2 (0.60) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL10250146 | 0.83 | LMNA (1.00) | MEN1KMT2ALMNAALDH1A1PTGES | |
| SCHEMBL2192252 | 0.83 | LMNA (0.71) | MEN1KMT2ALMNAALDH1A1TAS2R14 | |
| SCHEMBL2186013 | 0.82 | ALDH1A1 (0.77) | MEN1KMT2ALMNAALDH1A1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |