Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776393 | 0.88 | TP53 (0.72) | TP53MEN1KMT2ACNR1CNR2 | |
| SCHEMBL13064484 | 0.86 | MEN1 (0.78) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL13064515 | 0.81 | HTT (0.58) | KMT2AALDH1A1LMNA | |
| SCHEMBL13064477 | 0.80 | POLB (0.65) | TP53KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL13064516 | 0.78 | LMNA (0.60) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL3376969 | 0.78 | LMNA (0.60) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL13065202 | 0.78 | CNR2 (0.60) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL13064400 | 0.78 | POLB (0.59) | TP53KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL2189346 | 0.77 | LMNA (0.85) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3377704 | 0.76 | MEN1 (0.48) | MEN1KMT2ACNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |