Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064396 | 0.90 | LMNA (0.63) | CNR2LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL13065016 | 0.90 | CNR2 (0.56) | CNR2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL13065203 | 0.89 | PRKAA2 (0.55) | CNR2LMNAHTTKMT2AHPGD | |
| SCHEMBL13065210 | 0.87 | PKM (0.49) | CNR2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL302271 | 0.86 | LMNA (0.68) | CNR2LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL13064399 | 0.84 | CNR2 (0.48) | CNR2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL2773437 | 0.83 | CNR2 (0.60) | CNR2LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL13064397 | 0.83 | PKM (0.47) | CNR2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL13065015 | 0.82 | MEN1 (0.61) | CNR2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL13064394 | 0.82 | LMNA (0.52) | CNR2LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |