Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065016 | 0.91 | CNR2 (0.56) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13064488 | 0.90 | CNR2 (0.56) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065203 | 0.90 | PRKAA2 (0.55) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065210 | 0.88 | PKM (0.49) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065007 | 0.85 | LMNA (0.86) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13064399 | 0.85 | CNR2 (0.48) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL2773524 | 0.84 | LMNA (0.51) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13064397 | 0.84 | PKM (0.47) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065015 | 0.83 | MEN1 (0.61) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13064475 | 0.82 | SCD5 (0.47) | LMNAKMT2AHPGDCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |