Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | SCP2 | P22307 | 1/20 | 0.32 |
| ▸ | LRP6 | O75581 | 1/20 | 0.32 |
| ▸ | DKK1 | O94907 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065598 | 0.92 | MEN1 (0.43) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL16784717 | 0.90 | DHODH (0.39) | SLC16A3SNCAMAPTPOLBMEN1 | |
| SCHEMBL13065583 | 0.89 | PSMB5 (0.40) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL13065585 | 0.86 | SLC16A3 (0.38) | SLC16A3SNCAMAPTGPR119IKBKE | |
| SCHEMBL13065623 | 0.85 | MEN1 (0.41) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL16784744 | 0.84 | PDE10A (0.40) | MAPTPOLBMEN1NPC1RAB9A | |
| SCHEMBL13065622 | 0.83 | MEN1 (0.43) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL13065601 | 0.83 | KMT2A (0.43) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL13065605 | 0.83 | MEN1 (0.43) | SLC16A3MAPTPOLBMEN1NPC1 | |
| SCHEMBL13065591 | 0.83 | MEN1 (0.49) | SLC16A3MAPTPOLBMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | SLC16A3 4620/4885SNCA 3721/4885MAPT 3092/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | SLC16A3 4620/4885SNCA 3721/4885MAPT 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.