Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 5/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699087 | 0.80 | GAA (0.47) | LOXL2IDO1TAAR1GAAAGXT | |
| SCHEMBL23891925 | 0.78 | ABAT (0.50) | LOXL2TAAR1 | |
| SCHEMBL8337513 | 0.78 | CTBP2 (0.48) | LOXL2IDO1TAAR1GAAAGXT | |
| SCHEMBL10535299 | 0.78 | CA2 (0.60) | IDO1TAAR1CTBP2TDP1ALDH1A1 | |
| SCHEMBL9256936 | 0.78 | ALDH1A1 (0.48) | LOXL2GAAMAOAMAOBPOLB | |
| SCHEMBL13349456 | 0.77 | TAAR1 (0.52) | LOXL2IDO1TAAR1AGXTMAOA | |
| SCHEMBL328637 | 0.76 | CA2 (0.64) | LOXL2GAASMN1; SMN2CTBP2MAPK8 | |
| SCHEMBL183375 | 0.76 | IDO1 (0.57) | LOXL2IDO1TAAR1GAAAGXT | |
| SCHEMBL8033735 | 0.76 | CA2 (0.37) | — | |
| SCHEMBL8271141 | 0.76 | TDP1 (0.48) | LOXL2IDO1TAAR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |
| EP-1585522-B1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2010-11-17 | — | — | EP | disclosed |