SCHEMBL9256936

SCHEMBL9256936

C=C(N)Cc1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
GFER P55789 1/20 0.48
TSHR P16473 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.46
MAOB P27338 4/20 0.41
MAOA P21397 2/20 0.41
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA2 P00918 1/20 0.38
FDPS P14324 1/20 0.38
CA3 P07451 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
CA6 P23280 1/20 0.38
CASP1 P29466 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535299 0.80 CA2 (0.60) ALDH1A1TDP1GFERMAPTKMT2A
SCHEMBL23891925 0.80 ABAT (0.50) LOXL2CA2CA6CA14NOS1
SCHEMBL10339088 0.80 TDP1 (0.48) ALDH1A1CYP3A4TDP1GFERTSHR
SCHEMBL8033735 0.78 CA2 (0.37) CA2NOS1
SCHEMBL12942979 0.78 IDO1 (0.47) L3MBTL1
SCHEMBL24386036 0.78 IDO1 (0.47) TDP1CA2L3MBTL1
SCHEMBL13069072 0.78 LOXL2 (0.48) ALDH1A1TDP1LOXL2MAOBMAOA
SCHEMBL9485643 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1GFERTSHR
SCHEMBL11797216 0.78 CA2 (0.42) ALDH1A1CYP3A4TDP1GFERTSHR
SCHEMBL4958170 0.77 CES1 (0.50) ALDH1A1TSHRLOXL2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9846345-B2 Colored pigment particles for electrophoretic displays EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-12-19 US disclosed
US-20160018716-A1 COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS CRESTLINE DIRECT FINANCE, L.P. 2016-01-21 US disclosed
WO-2014133526-A1 COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-09-04 WO disclosed
EP-0505889-B1 Aqueous dispersions of encapsulated polyisocyanates BAYER AG (US) 1995-10-18 EP disclosed
EP-0505873-B1 A process for sealing and/or priming concrete with aqueous polyisocyanate dispersions and the concrete obtained by this process BAYER AG (US) 1995-08-23 EP disclosed
EP-0505871-B1 Process for preparing and optionally chain extending aqueous polyisocyanate dispersions using static mixers BAYER AG (US) 1995-08-02 EP disclosed
EP-0505875-B1 Aqueous polyisocyanate dispersions with reduced isocyanate contents and their use for the production of fiberglass mats MILES INC (US) 1995-07-12 EP disclosed
US-5428124-A Urea and biuret liquid prepolymers of MDI MILES INC. (US) 1995-06-27 US disclosed
US-5368806-A Polyurethanes with good molding properties and strength from diol and triols with isocyanates and amines MILES INC. (US) 1994-11-29 US disclosed
US-5221710-A PROCESS FOR PREPARING AND OPTIONALLY CHAIN EXTENDING AQUEOUS POLYISOCYANATE DISPERSIONS USING STATIC MIXERS MILES INC. (US) 1993-06-22 US disclosed
US-5191012-A AQUEOUS DISPERSIONS OF ENCAPSULATED POLYISOCYANATES MILES INC. (US) 1993-03-02 US disclosed
US-5185200-A AQUEOUS POLYISOCYANATE DISPERSIONS WITH REDUCED ISOCYANATE CONTENTS AND THEIR USE FOR THE PRODUCTION OF FIBERGLASS MATS MILES INC. (US) 1993-02-09 US disclosed
EP-0505889-A2 Aqueous dispersions of encapsulated polyisocyanates Bayer Corporation (US) 1992-09-30 EP disclosed
EP-0505871-A2 Process for preparing and optionally chain extending aqueous polyisocyanate dispersions using static mixers Bayer Corporation (US) 1992-09-30 EP disclosed
EP-0505875-A1 Aqueous polyisocyanate dispersions with reduced isocyanate contents and their use for the production of fiberglass mats Bayer Corporation (US) 1992-09-30 EP disclosed
EP-0505873-A1 A process for sealing and/or priming concrete with aqueous polyisocyanate dispersions and the concrete obtained by this process Bayer Corporation (US) 1992-09-30 EP disclosed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US disclosed