Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001854 | 0.98 | ALDH1A1 (0.70) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL27710661 | 0.90 | CYP2D6 (0.62) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL27690555 | 0.88 | HTR1A (0.62) | ALDH1A1KMT2AGFERMEN1TSHR | |
| SCHEMBL12267314 | 0.86 | ALDH1A1 (0.78) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL11755100 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL17033397 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL12240720 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AGFERLMNAMAPT | |
| Hydrochloric Acid SCHEMBL908555 | 0.85 | ALDH1A1 (0.79) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL12123614 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AGFERLMNAMAPT | |
| SCHEMBL7389787 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KMT2AGFERLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014091384-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | KANDULA MAHESH (IN) | 2014-06-19 | — | — | WO | disclosed |
| US-20140024677-A1 | METHODS FOR INDUCING MITOCHONDRIAL BIOGENESIS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024677-A1 | METHODS FOR INDUCING MITOCHONDRIAL BIOGENESIS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-01-23 | — | — | US | disclosed |
| EP-1401433-B1 | AZOLE ACID DERIVATIVES, ALONE OR IN COMBINATION, FOR TREATING DIABETES AND DYSLIPIDEMIAS; AND FOR TREATING MALIGNANT DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2010-11-10 | — | — | EP | disclosed |
| US-7452907-B2 | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452907-B2 | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024677-A1 | METHODS FOR INDUCING MITOCHONDRIAL BIOGENESIS | TFAM, TXNRD2, CPT1B | ALDH1A1 2635/4885KMT2A 2975/4885GFER 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.