Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248131 | 0.89 | — | — | |
| SCHEMBL10084447 | 0.77 | BACE1 (0.48) | BACE1BACE2 | |
| SCHEMBL8244815 | 0.74 | PGR (0.35) | BACE1BACE2 | |
| SCHEMBL13069251 | 0.74 | — | — | |
| SCHEMBL10074533 | 0.73 | BACE1 (0.42) | BACE1BACE2 | |
| SCHEMBL8247352 | 0.73 | BACE1 (0.48) | BACE1 | |
| SCHEMBL8244505 | 0.72 | BACE1 (0.43) | BACE1 | |
| SCHEMBL8238800 | 0.71 | NR1H2 (0.37) | BACE1BACE2 | |
| SCHEMBL10074528 | 0.71 | HCAR3 (0.36) | — | |
| SCHEMBL10074532 | 0.70 | BACE1 (0.34) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896430-B1 | THE PREPARATION AND USE OF COMPOUNDS AS ASPARTYL PROTEASE INHIBITORS | SCHERING CORP (US) | 2010-11-24 | — | — | EP | disclosed |