Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | SHBG | P04278 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | AR | P10275 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877448 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL27035399 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL15445000 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL22761988 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL37494 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28349042 | 0.99 | LMNA (0.98) | LMNANR3C1HIF1AMEN1KMT2A | |
| Acetic Acid SCHEMBL27624098 | 0.98 | LMNA (0.96) | LMNANR3C1HIF1AMEN1KMT2A | |
| Acetic Acid SCHEMBL609736 | 0.98 | LMNA (0.96) | LMNANR3C1HIF1AMEN1KMT2A | |
| Formic Acid SCHEMBL28467407 | 0.96 | LMNA (0.92) | LMNANR3C1HIF1AMEN1KMT2A | |
| Cyclopropane Carboxylic Acid SCHEMBL27035116 | 0.94 | LMNA (0.88) | LMNANR3C1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122096-A1 | PROCESS FOR OBTAINING FLUOROMETHOLONE AND INTERMEDIATES THEREFOR | CRYSTAL PHARMA, S.L.U. (ES) | 2010-10-28 | — | — | WO | disclosed |
| US-20090012321-A1 | PROCESS FOR PREPARING 17ALPHA-ACETOXY-6-METHYLENEPREGN-4-ENE-3,20-DIONE, MEDROXYPROGESTERONE ACETATE AND MEGESTROL ACETATE | BAYER SCHERING PHARMA AG (DE) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012321-A1 | PROCESS FOR PREPARING 17ALPHA-ACETOXY-6-METHYLENEPREGN-4-ENE-3,20-DIONE, MEDROXYPROGESTERONE ACETATE AND MEGESTROL ACETATE | CYP19A1, HSD17B11, CYP17A1 | LMNA 864/4885NR3C1 91/4885HIF1A 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.