Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | SHBG | P04278 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | AR | P10275 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035399 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL15445000 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL22761988 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL37494 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL13069287 | 1.00 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28349042 | 0.99 | LMNA (0.98) | LMNANR3C1HIF1AMEN1KMT2A | |
| Acetic Acid SCHEMBL27624098 | 0.98 | LMNA (0.96) | LMNANR3C1HIF1AMEN1KMT2A | |
| Acetic Acid SCHEMBL609736 | 0.98 | LMNA (0.96) | LMNANR3C1HIF1AMEN1KMT2A | |
| Formic Acid SCHEMBL28467407 | 0.96 | LMNA (0.92) | LMNANR3C1HIF1AMEN1KMT2A | |
| Cyclopropane Carboxylic Acid SCHEMBL27035116 | 0.94 | LMNA (0.88) | LMNANR3C1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277285-B1 | ESTRIOL FOR REDUCING CORTICAL GRAY MATTER ATROPHY | UNIV CALIFORNIA (US) | 2024-07-17 | — | — | EP | claimed |
| EP-3200802-B1 | COMPOSITIONS AND METHODS FOR MAINTAINING COGNITIVE FUNCTION | UNIV CALIFORNIA (US) | 2023-07-12 | — | — | EP | claimed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | claimed |
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | claimed |
| US-4014988-A | Method for treating hypermenorrhea with uterine therapeutic system | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | claimed |
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2024-01-25 | — | — | US | disclosed |
| US-11666584-B2 | Steroidal hormones for the treatment and prevention of wave burst arrhythmia | Assistance Publique—Hopitaux de Paris (FR) | 2023-06-06 | — | — | US | disclosed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-20200352960-A1 | STEROIDAL HORMONES FOR THE TREATMENT AND PREVENTION OF WAVE BURST ARRHYTHMIA | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) | 2020-11-12 | — | — | US | disclosed |
| EP-3188735-A1 | ESTROGEN THERAPY FOR BRAIN GRAY MATTER ATROPHY AND ASSOCIATED DISABILITY | The Regents of the University of California (US) | 2017-07-12 | — | — | EP | disclosed |
| US-4181721-A | Depot preparations in an oily, unsaturated solution for intramuscular injection | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | disclosed |
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |
| US-4154748-A | Phosphate catalyzed acylation of steroidal tertiary alcohols | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4066757-A | Oral contraceptive regimen | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4016270-A | Method for treating dysmenorrhea with a uterine therapeutic system | ALZA CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3993057-A | Intrauterine device that bioerodes in response to the environment of the uterus and method of using | ALZA CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
| US-3971367-A | Intrauterine device having means for changing from uterine-retentive shape to nonuterine-retentive shape | ALZA CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3935860-A | Intrauterine device with restrictor for maintaining device in uterine cavity | ALZA CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352960-A1 | STEROIDAL HORMONES FOR THE TREATMENT AND PREVENTION OF WAVE BURST ARRHYTHMIA | SHBG, NR5A1, HSD17B11 | LMNA 626/4885NR3C1 52/4885HIF1A 2048/4885 |
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HSD17B11, CYP19A1, CYP17A1 | LMNA 4253/4885NR3C1 90/4885HIF1A 1860/4885 |
| US-11666584-B2 | Steroidal hormones for the treatment and prevention of wave burst arrhythmia | SHBG, NR5A1, HSD17B11 | LMNA 626/4885NR3C1 52/4885HIF1A 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.