SCHEMBL37494

SCHEMBL37494

CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 1.00
NR3C1 P04150 4/20 1.00
HIF1A Q16665 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CYP2C19 P33261 3/20 1.00
MAPT P10636 2/20 1.00
CYP3A4 P08684 4/20 0.73
HSD17B10 Q99714 3/20 0.73
ALDH1A1 P00352 2/20 0.73
TSHR P16473 2/20 0.73
CYP2C9 P11712 1/20 0.73
SHBG P04278 4/20 0.71
PGR P06401 3/20 0.71
AR P10275 3/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
CHRM1 P11229 2/20 0.71
ABCC4 O15439 1/20 0.71
ABCB11 O95342 1/20 0.71
ESR1 P03372 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4877448 1.00 LMNA (1.00) LMNANR3C1HIF1AMEN1KMT2A
SCHEMBL27035399 1.00 LMNA (1.00) LMNANR3C1HIF1AMEN1KMT2A
SCHEMBL15445000 1.00 LMNA (1.00) LMNANR3C1HIF1AMEN1KMT2A
SCHEMBL22761988 1.00 LMNA (1.00) LMNANR3C1HIF1AMEN1KMT2A
SCHEMBL13069287 1.00 LMNA (1.00) LMNANR3C1HIF1AMEN1KMT2A
Hydrochloric Acid SCHEMBL28349042 0.99 LMNA (0.98) LMNANR3C1HIF1AMEN1KMT2A
Acetic Acid SCHEMBL27624098 0.98 LMNA (0.96) LMNANR3C1HIF1AMEN1KMT2A
Acetic Acid SCHEMBL609736 0.98 LMNA (0.96) LMNANR3C1HIF1AMEN1KMT2A
Formic Acid SCHEMBL28467407 0.96 LMNA (0.92) LMNANR3C1HIF1AMEN1KMT2A
Cyclopropane Carboxylic Acid SCHEMBL27035116 0.94 LMNA (0.88) LMNANR3C1HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26988 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
EP-4735116-A2 ANTI-TRAILR2 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2026-05-06 EP claimed
US-12606797-B2 Methods of detection of mechanically-activated platelet activation and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-04-21 US claimed
US-20260091041-A1 Methods of Treating Heavy Menstrual Bleeding ABBVIE INC (US) 2026-04-02 US claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
US-12508236-B2 Solid nanoparticle with inorganic coating NANEXA AB (SE) 2025-12-30 US claimed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
US-20250378952-A1 METHODS FOR DETERMINING MENSTRUAL CYCLE TIME POINT THE UNIVERSITY OF MELBOURNE (AU) 2025-12-11 US claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
WO-1987005804-A1 METHYLPREDNISOLONE/SODIUM CARBOXYMETHYL STARCH TABLET COMPOSITION THE UPJOHN COMPANY (US) 1987-10-08 WO claimed
EP-0123528-B1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF HAIR LOSS Mortimer, Christopher Harry, Dr. (GB) 1987-09-09 EP claimed
EP-0123528-A1 Pharmaceutical composition for the treatment of hair loss Mortimer, Christopher Harry, Dr. (GB) 1984-10-31 EP claimed
WO-1984004038-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF HAIR LOSS MORTIMER CHRISTOPHER HARRY (GB) 1984-10-25 WO claimed
US-4381298-A Oral male contraceptive composition COULSON PATRICIA B 1983-04-26 US claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4177269-A ANTITUMOR AGENTS AKTIEBOLAGET LEO (SE) 1979-12-04 US claimed
US-4041055-A SULFENYLATION, MICHAEL ADDITION, REACTION WITH THIOPHILE, HYDROLYSIS THE UPJOHN COMPANY (US) 1977-08-09 US claimed
US-4016251-A Vaginal drug dispensing device ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US claimed