SCHEMBL13069412

SCHEMBL13069412

Cc1cc(C(c2cc(C)c(N)c(C)c2)c2c(Cl)cccc2Cl)cc(C)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
CYP1A1 P04798 1/20 0.40
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 5/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PLA2G7 Q13093 1/20 0.36
NR4A2 P43354 2/20 0.34
CD44 P16070 2/20 0.33
GAA P10253 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
PNMT P11086 1/20 0.32
POLB P06746 1/20 0.32
PIK3CA P42336 1/20 0.32
SRC P12931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14085394 0.79 PNMT (0.42) CYP1A2ALDH1A1CYP3A4TSHRTP53
SCHEMBL12374450 0.77 POLB (0.36) CYP1A2CYP1A1ALDH1A1CYP3A4GAA
SCHEMBL13636830 0.77 ALDH1A1 (0.32) CYP1A2CYP1A1ALDH1A1
SCHEMBL28205472 0.72 ALDH1A1 (0.42) CYP1A2CYP1A1ALDH1A1CYP3A4TSHR
SCHEMBL5011789 0.72 CYP3A4 (0.39) CYP1A2ALDH1A1CYP3A4TSHRPLA2G7
SCHEMBL3687485 0.72 ALDH1A1 (0.42) CYP1A2CYP1A1ALDH1A1CYP3A4TSHR
SCHEMBL4078435 0.72 CYP1A2 (0.50) CYP1A2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL21793853 0.72 CYP1A1 (0.31) CYP1A2CYP1A1PLA2G7
SCHEMBL11674942 0.72 KDM4E (0.46) CYP1A2ALDH1A1CYP3A4TSHRLMNA
SCHEMBL3688289 0.71 LMNA (0.42) CYP1A2CYP1A1ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1956054-B1 Phase change ink XEROX CORP (US) 2010-11-24 EP disclosed
EP-1958993-A1 Phase change inks containing colorant compounds Xerox Corporation (US) 2008-08-20 EP disclosed
EP-1956054-A2 Colorant compounds Xerox Corporation (US) 2008-08-13 EP disclosed
US-20080187664-A1 Phase change inks containing colorant compounds XEROX CORPORATION 2008-08-07 US disclosed
US-20080187664-A1 Phase change inks containing colorant compounds XEROX CORPORATION 2008-08-07 US disclosed
US-20080184910-A1 Mixture of basic dye and wax XEROX CORPORATION 2008-08-07 US disclosed
US-20080184910-A1 Mixture of basic dye and wax XEROX CORPORATION 2008-08-07 US disclosed