Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.81 |
| ▸ | PGR | P06401 | 6/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.81 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | AR | P10275 | 3/20 | 0.77 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL6 | P05231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271565 | 1.00 | HIF1A (0.81) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL3397738 | 1.00 | HIF1A (0.81) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL3397741 | 1.00 | HIF1A (0.81) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL3406698 | 0.92 | CYP3A4 (0.81) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL3406702 | 0.92 | CYP3A4 (0.81) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL11691405 | 0.90 | CYP3A4 (0.78) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL11691394 | 0.90 | CYP3A4 (0.78) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| SCHEMBL21145516 | 0.90 | CYP3A4 (0.78) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| Methylprednisolone SCHEMBL541256 | 0.89 | HIF1A (1.00) | HIF1ACYP3A4PGRNR3C1HSD17B10 | |
| Methylprednisolone SCHEMBL21145528 | 0.89 | HIF1A (1.00) | HIF1ACYP3A4PGRNR3C1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122096-A1 | PROCESS FOR OBTAINING FLUOROMETHOLONE AND INTERMEDIATES THEREFOR | CRYSTAL PHARMA, S.L.U. (ES) | 2010-10-28 | — | — | WO | disclosed |