Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.78 |
| ▸ | PGR | P06401 | 6/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.78 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.72 |
| ▸ | F2 | P00734 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | GLUL | P15104 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798815 | 0.94 | CYP3A4 (0.74) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL10798820 | 0.94 | CYP3A4 (0.74) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL10944298 | 0.90 | HIF1A (0.70) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL6835391 | 0.90 | CYP3A4 (0.72) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL9602408 | 0.90 | CYP3A4 (0.72) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL3397738 | 0.90 | HIF1A (0.81) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL3397741 | 0.90 | HIF1A (0.81) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL11271565 | 0.90 | HIF1A (0.81) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL3406702 | 0.90 | CYP3A4 (0.81) | CYP3A4HIF1APGRNR3C1HSD17B10 | |
| SCHEMBL3406698 | 0.90 | CYP3A4 (0.81) | CYP3A4HIF1APGRNR3C1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216823-A1 | METHYLPREDNISOLONE PHARMACEUTICAL SUSPENSION | HYLORIS DEVELOPMENTS SA (BE) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216823-A1 | METHYLPREDNISOLONE PHARMACEUTICAL SUSPENSION | NR3C1, MC2R, SERPINA6 | CYP3A4 92/4885HIF1A 4217/4885PGR 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.