Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894799 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTCASP6MEN1 | |
| SCHEMBL10073821 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTCASP6MEN1 | |
| SCHEMBL5807693 | 0.79 | HTT (0.51) | ALDH1A1L3MBTL1HTTLMNAGAA | |
| SCHEMBL5808231 | 0.79 | TSHR (0.36) | ALDH1A1KMT2AMAPTCASP6MEN1 | |
| SCHEMBL2911214 | 0.78 | ALOX5 (0.50) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| Water SCHEMBL17476087 | 0.78 | TSHR (0.35) | ALDH1A1KMT2AMAPTCASP6MEN1 | |
| SCHEMBL13539495 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTCASP6L3MBTL1 | |
| SCHEMBL12947975 | 0.77 | NT5E (0.47) | ALDH1A1CASP6HTTCYP2C9CYP2C19 | |
| SCHEMBL11509483 | 0.76 | MAPT (0.47) | ALDH1A1KMT2AMAPTCASP6MEN1 | |
| SCHEMBL5803930 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251385-A1 | Pyrazolone bisazo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251382-A1 | Monoazo compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251384-A1 | Pyrazolone monoazo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251386-A1 | Pyrazolone bisazo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251381-A1 | Monoazo compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |