Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435978 | 0.87 | LMNA (0.51) | L3MBTL1OPRM1NPC1ALDH1A1LMNA | |
| SCHEMBL28171784 | 0.83 | KDM4E (0.51) | HTTL3MBTL1KDM4ENPC1ALDH1A1 | |
| SCHEMBL4917405 | 0.81 | KDM4E (0.50) | KDM4EOPRM1NPC1POLBALDH1A1 | |
| SCHEMBL11334891 | 0.80 | CYP1A2 (0.49) | HTTL3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL13070263 | 0.79 | ALDH1A1 (0.42) | HTTL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL10707004 | 0.77 | POLB (0.60) | HTTKDM4ENPC1POLBALDH1A1 | |
| SCHEMBL15428601 | 0.77 | HTT (0.52) | HTTL3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL31522200 | 0.75 | ALDH1A1 (0.58) | HTTKDM4EESR1JAK2JAK1 | |
| SCHEMBL31522201 | 0.75 | ALDH1A1 (0.58) | HTTKDM4EESR1JAK2JAK1 | |
| SCHEMBL13902297 | 0.75 | ALDH1A1 (0.50) | HTTL3MBTL1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| WO-2006091023-A1 | ANTIBACTERIAL ACID DYES CONTAINING SILVER AND METHOD OF PREPARING THE SAME AND ANTIBACTERIAL FIBER THEREBY | KOLON INDUSTRIES, INC (KR) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | KRT18, LPO, KRTCAP2 | HTT 1138/4885L3MBTL1 4255/4885KDM4E 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.