Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070610 | 0.82 | STS (0.39) | MEN1KMT2ASTSSMN1; SMN2MAPT | |
| SCHEMBL17656252 | 0.82 | CBX7 (0.40) | STSSMN1; SMN2MAPTTTRHTR2B | |
| SCHEMBL204756 | 0.75 | PTPN1 (0.50) | SMN1; SMN2MAPTTTRHTR2BKDM4E | |
| SCHEMBL11864035 | 0.75 | TTR (0.65) | MEN1KMT2ASTSTTRKDM4E | |
| SCHEMBL10992173 | 0.75 | TTR (0.55) | MEN1KMT2ASTSSMN1; SMN2MAPT | |
| SCHEMBL16806149 | 0.73 | HSD17B3 (0.55) | ATMMEN1KMT2ASTSSMN1; SMN2 | |
| SCHEMBL15040999 | 0.72 | NPC1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTTTR | |
| SCHEMBL11843291 | 0.71 | XDH (0.45) | SMN1; SMN2L3MBTL1ALDH1A1HPGDNPC1 | |
| SCHEMBL30175920 | 0.70 | TTR (0.68) | MEN1KMT2ASMN1; SMN2MAPTTTR | |
| SCHEMBL69226 | 0.70 | TTR (0.68) | MEN1KMT2ASMN1; SMN2MAPTTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |