SCHEMBL13070844

SCHEMBL13070844

Cc1cc(C)n2nc(S)c(S(=O)(=O)c3cccc(F)c3)c2n1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 0.72
HTR2B P41595 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13016788 0.88 HTR6 (0.76) HTR6HTR2B
SCHEMBL13070846 0.87 HTR6 (0.71) HTR6HTR2B
SCHEMBL13070640 0.87 HTR6 (0.76) HTR6HTR2B
SCHEMBL13070637 0.86 HTR6 (0.72) HTR6HTR2B
SCHEMBL15303981 0.84 HTR6 (0.70) HTR6HTR2B
SCHEMBL8032114 0.84 HTR6 (1.00) HTR6HTR2B
SCHEMBL8043751 0.84 HTR6 (0.77) HTR6HTR2B
SCHEMBL13016752 0.84 HTR6 (1.00) HTR6
SCHEMBL13016753 0.81 HTR6 (0.79) HTR6HTR2B
SCHEMBL13070358 0.76 HTR6 (0.80) HTR6HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248815-A2 3-SULFONYL-PYRAZOLO[1,5-A]PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF Alla Chem, LLC. (US) 2010-11-10 EP disclosed