Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031010 | 0.88 | HTR6 (0.79) | HTR6HTR2B | |
| SCHEMBL8041753 | 0.87 | HTR6 (0.78) | HTR6HTR2B | |
| SCHEMBL8044428 | 0.87 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL13016788 | 0.86 | HTR6 (0.76) | HTR6HTR2B | |
| SCHEMBL13070844 | 0.84 | HTR6 (0.72) | HTR6HTR2B | |
| SCHEMBL8032114 | 0.82 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL13016752 | 0.82 | HTR6 (1.00) | HTR6 | |
| SCHEMBL15303981 | 0.82 | HTR6 (0.70) | HTR6HTR2B | |
| SCHEMBL13016753 | 0.80 | HTR6 (0.79) | HTR6HTR2B | |
| SCHEMBL13043462 | 0.75 | HTR6 (1.00) | HTR6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248817-B1 | SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM LLC (US) | 2015-01-07 | — | — | EP | claimed |
| US-8829009-B2 | Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof | IVASHTCHENKO ALEXANDER VASILLEVICH (US) | 2014-09-09 | — | — | US | claimed |
| US-20130079350-A1 | Substitute 2-amino-3-(Sulfony)pyrazol[1,5-a]pyramidines - serotonin 5-ht6 receptor antagonists, method for us thereof | Ivashtchenko Alexander Vasilievich (US) | 2013-03-28 | — | — | US | claimed |
| US-8309559-B2 | (EN) substituted 2-amino-3-sulfonyl-pyrazolo[1,5-A] pyrimidines/antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | SAVCHUK NIKOLAY FILIPPOVICH (US) | 2012-11-13 | — | — | US | claimed |
| EP-2248817-B1 | SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM LLC (US) | 2015-01-07 | — | — | EP | disclosed |
| US-8829009-B2 | Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof | IVASHTCHENKO ALEXANDER VASILLEVICH (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829009-B2 | Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof | IVASHTCHENKO ALEXANDER VASILLEVICH (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829009-B2 | Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof | IVASHTCHENKO ALEXANDER VASILLEVICH (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130079350-A1 | Substitute 2-amino-3-(Sulfony)pyrazol[1,5-a]pyramidines - serotonin 5-ht6 receptor antagonists, method for us thereof | Ivashtchenko Alexander Vasilievich (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079350-A1 | Substitute 2-amino-3-(Sulfony)pyrazol[1,5-a]pyramidines - serotonin 5-ht6 receptor antagonists, method for us thereof | Ivashtchenko Alexander Vasilievich (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079350-A1 | Substitute 2-amino-3-(Sulfony)pyrazol[1,5-a]pyramidines - serotonin 5-ht6 receptor antagonists, method for us thereof | Ivashtchenko Alexander Vasilievich (US) | 2013-03-28 | — | — | US | disclosed |
| US-8309559-B2 | (EN) substituted 2-amino-3-sulfonyl-pyrazolo[1,5-A] pyrimidines/antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | SAVCHUK NIKOLAY FILIPPOVICH (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309559-B2 | (EN) substituted 2-amino-3-sulfonyl-pyrazolo[1,5-A] pyrimidines/antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | SAVCHUK NIKOLAY FILIPPOVICH (US) | 2012-11-13 | — | — | US | disclosed |
| US-20100292245-A1 | (EN) SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | IVASHCHENKO ANDREY ALEXANDROVICH | 2010-11-18 | — | — | US | disclosed |
| US-20100292245-A1 | (EN) SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | IVASHCHENKO ANDREY ALEXANDROVICH | 2010-11-18 | — | — | US | disclosed |
| EP-2248817-A2 | SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | Alla Chem, LLC. (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009093208-A2 | SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292245-A1 | (EN) SUBSTITUTED 2-AMINO-3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | HTR6, HTR1A, HTR1F | HTR6 1/4885HTR2B 14/4885 |
| US-20130079350-A1 | Substitute 2-amino-3-(Sulfony)pyrazol[1,5-a]pyramidines - serotonin 5-ht6 receptor antagonists, method for us thereof | HTR5A, HTR6, HTR1A | HTR6 2/4885HTR2B 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.