Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303980 | 0.89 | HTR6 (0.82) | HTR6HTR2B | |
| SCHEMBL13016755 | 0.88 | HTR6 (0.80) | HTR6HTR2B | |
| SCHEMBL13016752 | 0.88 | HTR6 (1.00) | HTR6 | |
| SCHEMBL13016750 | 0.88 | HTR6 (0.83) | HTR6HTR2B | |
| SCHEMBL13016747 | 0.88 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL13016791 | 0.84 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL13016788 | 0.83 | HTR6 (0.76) | HTR6HTR2B | |
| SCHEMBL13070844 | 0.81 | HTR6 (0.72) | HTR6HTR2B | |
| SCHEMBL13016798 | 0.80 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL8043751 | 0.80 | HTR6 (0.77) | HTR6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248815-B1 | 3-SULFONYL-PYRAZOLO[1,5-A]PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | AVINEURO PHARMACEUTICALS INC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8552005-B2 | (EN) 3-sulfonyl-pyrazolo[1,5-a] pyrimidines / antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | Avincuro Pharmaceuticals, Inc. (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552005-B2 | (EN) 3-sulfonyl-pyrazolo[1,5-a] pyrimidines / antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | Avincuro Pharmaceuticals, Inc. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20100331347-A1 | (EN) 3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | AVINEURO PHARMACEUTICALS, INC. | 2010-12-30 | — | — | US | disclosed |
| US-20100331347-A1 | (EN) 3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | AVINEURO PHARMACEUTICALS, INC. | 2010-12-30 | — | — | US | disclosed |
| EP-2248815-A2 | 3-SULFONYL-PYRAZOLO[1,5-A]PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | Alla Chem, LLC. (US) | 2010-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331347-A1 | (EN) 3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | HTR6, HTR1A, HTR3A | HTR6 1/4885HTR2B 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.