Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756772 | 0.94 | HTR2A (0.33) | HTR2AHTR2CLMNATRPA1PTGS1 | |
| SCHEMBL2707193 | 0.91 | HSD17B10 (0.33) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL2756742 | 0.85 | MAPT (0.34) | HTR2AHTR2CLMNAHSD17B10 | |
| SCHEMBL18542710 | 0.84 | LMNA (0.36) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL6509446 | 0.82 | MAPT (0.38) | HTR2AHTR2CLMNAHSD17B10 | |
| SCHEMBL13070864 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL15855088 | 0.80 | PDK2 (0.41) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL17656226 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL7521829 | 0.78 | LMNA (0.36) | HTR2AHTR2CLMNATRPA1HPGD | |
| SCHEMBL9188443 | 0.77 | GAA (0.38) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |