SCHEMBL7521829

SCHEMBL7521829

Cc1ccc2c(c1)Oc1cc(C)ccc1C2(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
THRB P10828 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP19A1 P11511 1/20 0.34
CNR2 P34972 3/20 0.33
ALDH1A1 P00352 3/20 0.33
ALDH2 P05091 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2756742 0.92 MAPT (0.34) LMNATHRBTDP1TP53SMN1; SMN2
SCHEMBL9188748 0.90 LMNA (0.41) LMNATDP1SMN1; SMN2KMT2ACYP19A1
SCHEMBL22991300 0.89 LMNA (0.31) LMNAHTR2AHTR2C
Phenol SCHEMBL27442366 0.86 LMNA (0.41) LMNATDP1SMN1; SMN2ALOX15CYP1A2
SCHEMBL19765424 0.86 TDP1 (0.31) LMNATHRBTDP1TP53SMN1; SMN2
SCHEMBL7784008 0.84 CYP19A1 (0.37) LMNACYP19A1ALDH1A1ALDH2GAA
SCHEMBL6509446 0.82 MAPT (0.38) LMNATHRBTDP1TP53SMN1; SMN2
SCHEMBL2756772 0.82 HTR2A (0.33) LMNAHTR2AHTR2CTRPA1HPGD
SCHEMBL9188443 0.78 GAA (0.38) LMNATHRBTDP1SMN1; SMN2CYP2A6
SCHEMBL13071040 0.78 HTR2A (0.33) LMNAHTR2AHTR2CTRPA1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1139107-A Method for recovering phenol and xanthene values from waste polycarbonate GEN ELECTRIC (US) 1997-01-01 CN claimed
EP-0738702-A1 Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP claimed
US-5567829-A Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-22 US claimed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US claimed
JP-9003056-A None JP disclosed
US-10680184-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-10680184-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-20180013075-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-01-11 US disclosed
US-20180013075-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-01-11 US disclosed
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
EP-0738723-B1 Method for making polyalkylated xanthenes GEN ELECTRIC (US) 2002-03-13 EP disclosed
JP-H093056-A PRODUCTION OF POLYALKYLATED XANTHENE GENERAL ELECTRIC CO <GE> 1997-01-07 JP disclosed
CN-1139107-A Method for recovering phenol and xanthene values from waste polycarbonate GEN ELECTRIC (US) 1997-01-01 CN disclosed
EP-0738723-A2 Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
EP-0738702-A1 Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
US-5567829-A Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-22 US disclosed
US-5554770-A Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-09-10 US disclosed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180013075-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ANKK1, EYA2, KCNN2 LMNA 1887/4885THRB 3545/4885TDP1 1264/4885
US-10680184-B2 Organic electroluminescent materials and devices ANKK1, EYA2, KCNN2 LMNA 1887/4885THRB 3545/4885TDP1 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.