Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726541 | 0.87 | OXER1 (0.35) | TSHRPOLBPOLA1 | |
| SCHEMBL9726544 | 0.87 | OXER1 (0.35) | TSHRPOLBPOLA1 | |
| SCHEMBL28243 | 0.81 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11580988 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL10347529 | 0.75 | ALDH1A1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL28909844 | 0.75 | — | — | |
| SCHEMBL11551166 | 0.74 | POLB (0.52) | TSHRPOLBPOLA1HSD17B10MGAM | |
| SCHEMBL2592556 | 0.74 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8136448 | 0.74 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL15976653 | 0.73 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131738-A1 | AZETIDINE COMPOUND AND MEDICINAL USE THEREOF | 日本たばこ産業株式会社 (JP) | 2010-11-18 | — | — | WO | disclosed |