Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.45 |
| ▸ | ODC1 | P11926 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666280 | 0.94 | COXFA4 (0.61) | COXFA4HSP90AA1HIF1AODC1ALDH1A1 | |
| SCHEMBL12315603 | 0.92 | COXFA4 (0.57) | COXFA4HSP90AA1HIF1AALDH1A1CYP3A4 | |
| SCHEMBL14139185 | 0.81 | COXFA4 (1.00) | COXFA4HSP90AA1HIF1AODC1PDE7A | |
| SCHEMBL12315566 | 0.80 | COXFA4 (0.68) | COXFA4HSP90AA1HIF1AODC1PDE7A | |
| SCHEMBL12315467 | 0.80 | COXFA4 (0.46) | COXFA4HIF1AALDH1A1CYP3A4HPGD | |
| SCHEMBL13071290 | 0.80 | COXFA4 (0.46) | COXFA4HIF1AALDH1A1CYP3A4HPGD | |
| SCHEMBL14666188 | 0.77 | HSP90AA1 (0.54) | COXFA4HSP90AA1HIF1AALDH1A1CYP3A4 | |
| SCHEMBL14098877 | 0.76 | COXFA4 (0.89) | COXFA4HSP90AA1HIF1AODC1PDE7A | |
| SCHEMBL12315602 | 0.73 | COXFA4 (0.84) | COXFA4HSP90AA1HIF1A | |
| SCHEMBL14139261 | 0.71 | COXFA4 (0.81) | COXFA4HSP90AA1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253333-A2 | Contrast Agents for Myocardial Perfusion Imaging | Lantheus Medical Imaging, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |