Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.89 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ODC1 | P11926 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139185 | 0.94 | COXFA4 (1.00) | COXFA4HSP90AA1HIF1AEPAS1HTT | |
| SCHEMBL12315602 | 0.90 | COXFA4 (0.84) | COXFA4HSP90AA1HIF1AEPAS1 | |
| SCHEMBL14098881 | 0.88 | COXFA4 (0.74) | COXFA4HSP90AA1HIF1AEPAS1 | |
| SCHEMBL14139261 | 0.86 | COXFA4 (0.81) | COXFA4HSP90AA1HIF1AEPAS1 | |
| SCHEMBL14666280 | 0.83 | COXFA4 (0.61) | COXFA4HSP90AA1HIF1AEPAS1ODC1 | |
| SCHEMBL12315552 | 0.79 | COXFA4 (0.74) | COXFA4HSP90AA1HIF1A | |
| SCHEMBL14666128 | 0.79 | COXFA4 (0.58) | COXFA4HSP90AA1HIF1AEPAS1ODC1 | |
| SCHEMBL12315607 | 0.77 | HIF1A (0.56) | COXFA4HSP90AA1HIF1AEPAS1ODC1 | |
| SCHEMBL12315469 | 0.76 | COXFA4 (0.66) | COXFA4HIF1AEPAS1 | |
| SCHEMBL12315566 | 0.76 | COXFA4 (0.68) | COXFA4HSP90AA1HIF1AHTTODC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-7410998-B2 | Inhibitors of NADH:ubiquinone oxidoreductase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | COXFA4 2119/4885HSP90AA1 1970/4885HIF1A 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.