Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306111 | 0.93 | PTPN1 (0.46) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL1306520 | 0.89 | ADAMTS5 (0.41) | ALDH1A1KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL1306700 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL1306696 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL1307179 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL1307180 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL1306562 | 0.85 | HPGD (0.44) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL1306200 | 0.84 | HPGD (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL1305940 | 0.84 | GAA (0.43) | ALDH1A1KDM4EKMT2AHPGDTDP1 | |
| SCHEMBL1306596 | 0.84 | ADAMTS5 (0.39) | ALDH1A1KDM4EMEN1KMT2ACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |