Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 4/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071408 | 0.94 | XIAP (0.33) | XIAPUBE2MDCUN1D1S1PR2 | |
| SCHEMBL12831737 | 0.86 | F2 (0.34) | XIAP | |
| SCHEMBL13071885 | 0.85 | XIAP (0.35) | XIAP | |
| SCHEMBL13071474 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL13071626 | 0.85 | DPP4 (0.36) | XIAP | |
| SCHEMBL13072078 | 0.85 | XIAP (0.33) | XIAP | |
| SCHEMBL13071393 | 0.84 | DPP4 (0.32) | XIAPUBE2MDCUN1D1 | |
| SCHEMBL13071403 | 0.83 | USP2 (0.34) | — | |
| SCHEMBL12831783 | 0.82 | F2R (0.34) | XIAP | |
| SCHEMBL13072075 | 0.81 | XIAP (0.31) | XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142842-A9 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2009142842-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-26 | — | — | WO | disclosed |