Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400169 | 0.87 | CDK2 (0.38) | DGAT1 | |
| SCHEMBL401078 | 0.83 | SMN1; SMN2 (0.35) | DGAT1 | |
| SCHEMBL401945 | 0.82 | MAPT (0.34) | DGAT1 | |
| SCHEMBL1056138 | 0.79 | PDE10A (0.33) | — | |
| SCHEMBL15016442 | 0.75 | GRM5 (0.38) | DGAT1 | |
| SCHEMBL3496820 | 0.74 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL3529847 | 0.74 | ABL1 (0.35) | — | |
| SCHEMBL27076442 | 0.74 | CACNA1G (0.40) | — | |
| SCHEMBL3527752 | 0.73 | — | — | |
| SCHEMBL1052514 | 0.71 | GPR4 (0.32) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834018-B2 | aurora kinase inhibitors; 2-(thiazol-2-ylamino)pyridine compounds as antitumor agents; 6-((4-(3-chloro-2-fluorobenzoyl)piperazin-1-yl)methyl)-N-thiazol-2-ylpyridin-2-amine for example | BANYU PHARMACEUTICAL CO., LTD (JP) | 2010-11-16 | — | — | US | disclosed |