Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400138 | 0.94 | HSD17B10 (0.53) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3402499 | 0.87 | CYP1A2 (0.53) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3406018 | 0.86 | HSD17B10 (0.49) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3401951 | 0.86 | HSD17B10 (0.49) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL13071564 | 0.85 | DRD2 (0.47) | — | |
| SCHEMBL3400825 | 0.85 | CYP1A2 (0.54) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3399723 | 0.84 | HSD17B10 (0.51) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3402383 | 0.84 | HSD17B10 (0.51) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL13071989 | 0.82 | CHRM4 (0.47) | — | |
| SCHEMBL3400068 | 0.82 | CYP1A2 (0.58) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297035-A1 | Thiazole Amides, Imidazole Amides and Related Analogues | LIGAND PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297035-A1 | Thiazole Amides, Imidazole Amides and Related Analogues | HRH3, HRH4, HRH2 | HSD17B10 3129/4885CYP1A2 1326/4885CYP2D6 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.