Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620598 | 0.76 | HCAR2 (0.37) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL734433 | 0.71 | HCAR2 (0.35) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL8680389 | 0.68 | HCAR2 (0.34) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL6759519 | 0.68 | HCAR2 (0.36) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL2646503 | 0.67 | MEN1 (0.38) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL24228671 | 0.67 | TNF (0.35) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL24228647 | 0.67 | HCAR2 (0.35) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL4548482 | 0.64 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL4548465 | 0.64 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13072042 | 0.63 | TRIM24 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134939-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2010-11-25 | — | — | WO | disclosed |