SCHEMBL8680389

SCHEMBL8680389

CC1CCC(C(=O)OC(=O)C2=C(C(=O)O)CC(C)CC2)=C(C(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.34
ALDH1A1 P00352 5/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
KDM4E B2RXH2 3/20 0.33
ALOX15 P16050 3/20 0.33
HSD17B10 Q99714 3/20 0.33
KMT2A Q03164 2/20 0.33
ALOX12 P18054 2/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
USP2 O75604 1/20 0.31
MEN1 O00255 1/20 0.31
TLR4 O00206 1/20 0.30
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620598 0.86 HCAR2 (0.37) HCAR2ALDH1A1MAPTHPGDKDM4E
Calcium SCHEMBL30537018 0.84 HCAR2 (0.36) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL28692905 0.84 HCAR2 (0.36) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL2646503 0.80 MEN1 (0.38) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL734433 0.77 HCAR2 (0.35) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL7283619 0.76
SCHEMBL7977219 0.75 CRBN (0.38) HCAR2ALDH1A1KDM4EHSD17B10GAA
SCHEMBL6759519 0.75 HCAR2 (0.36) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL7950768 0.74 ALDH1A1 (0.39) HCAR2ALDH1A1MAPTHPGDKDM4E
SCHEMBL24228647 0.73 HCAR2 (0.35) HCAR2ALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4191695-A WATER EXCHANGE BETWEEN MALEIC ACID AND A CARBOXYLIC ANHYDRIDE LONZA LTD. (CH) 1980-03-04 US claimed
CN-113039312-B Poly alpha-olefin modified polymer blends for fibers and nonwovens 埃克森美孚化学专利公司 2023-10-10 CN disclosed
CN-116529431-A Nonwoven fabric with improved touch and mechanical properties 埃克森美孚化学专利公司 2023-08-01 CN disclosed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN disclosed
CN-115867589-A Thermosetting resin composition 亨斯迈先进材料美国有限责任公司 2023-03-28 CN disclosed
CN-115135700-A Toughened thermosetting resin composition 亨斯迈先进材料美国有限责任公司 2022-09-30 CN disclosed
CN-111511776-B Metallocene catalyst feed system for solution polymerization process 埃克森美孚化学专利公司 2022-09-16 CN disclosed
CN-114829486-A Functionalized propylene-based elastomer compositions and methods of making the same 埃克森美孚化学专利公司 2022-07-29 CN disclosed
CN-114787271-A Propylene-based elastomer compositions, articles thereof, and methods thereof 埃克森美孚化学专利公司 2022-07-22 CN disclosed
CN-114746504-A Curable resin compositions containing aliphatic polyketone tougheners and composites prepared therefrom 亨斯迈先进材料美国有限责任公司 2022-07-12 CN disclosed
CN-104264305-A Fabric Including Polylefin Elastic Fiber INVISTA TECH SARL 2015-01-07 CN disclosed
CN-104010808-A Fibers and nonwoven materials prepared thereform EXXON MOBIL CHEM PATENTS INC 2014-08-27 CN disclosed
CN-103635619-A Elastic nonwoven material comprising propylene-based and ethylene-based polymers EXXON MOBIL CHEM PATENTS INC 2014-03-12 CN disclosed
CN-103201416-A Bicomponent fibers and method of making same EXXONMOBIL CHEM PATENTS INC 2013-07-10 CN disclosed
CN-102770590-A Fabric comprising polyolefin elastic fibers INVISTA TECH SARL 2012-11-07 CN disclosed
CN-102762176-A Stretch articles comprising polyolefin elastic fibers INVISTA TECH SARL 2012-10-31 CN disclosed
US-5707732-A Flame retardant cable NIPPON UNICAR COMPANY LIMITED (JP) 1998-01-13 US disclosed
US-5296452-A Herbicidal 3-(3,4,5,6-tetrahydrophthalimido)-cinnamic esters BASF AKTIENGESELLSCHAFT (DE) 1994-03-22 US disclosed
US-4615968-A ALIPHATIC UNSATURATED POLYCONDENSATION PRODUCT AND A BISIMIDE CIBA-GEIGY CORPORATION (US) 1986-10-07 US disclosed
US-4191695-A WATER EXCHANGE BETWEEN MALEIC ACID AND A CARBOXYLIC ANHYDRIDE LONZA LTD. (CH) 1980-03-04 US disclosed