Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307099 | 0.92 | PTPN1 (0.48) | LMNAMAPTHTTALDH1A1KDM4E | |
| SCHEMBL1307912 | 0.91 | LMNA (0.51) | LMNASMN1; SMN2TDP1MAPTHTT | |
| SCHEMBL1307916 | 0.91 | LMNA (0.51) | LMNASMN1; SMN2TDP1MAPTHTT | |
| SCHEMBL1306130 | 0.89 | P2RX3 (0.46) | LMNASMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL1306132 | 0.89 | P2RX3 (0.46) | LMNASMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL1306801 | 0.86 | KDM4E (0.47) | LMNASMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL1306788 | 0.85 | PTPN1 (0.48) | LMNASMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL1306787 | 0.85 | PTPN1 (0.48) | LMNASMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL1307208 | 0.84 | TRPM4 (0.41) | LMNASMN1; SMN2TDP1MAPTHTT | |
| SCHEMBL1306614 | 0.83 | HDAC3 (0.47) | LMNAMAPTALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |